The Solution to Resistant Hypertension Treatment is Cold!
CRYOVASC´s Renal Freezer
Just One Cold Beam and
High-Blood Pressure is Gone.
The Most Powerful Blood-Pressure Drop Ever Measured in Renal Denervation.
Maximum precision combined with a softer, tissue-sparing approach that is safer than anything before.
Most existing renal denervation systems use heat to destroy the nerves around the renal artery. Our Cryo-RDN technology works differently: we cool it down to very low, sub-zero temperatures.
Our controlled cold treatment targets the renal nerves surrounding the artery in a precise and gentle way, without using heat.
Best of all, only one balloon inflation per renal artery is needed — making the procedure simpler, faster, and eliminating the need for repeated denervations.
Animal Study Published
Peer-Reviewed in JACC.
"Preclinical Evaluation of a
Novel Cryo Renal Denervation System"
"In the porcine model, Cryo-RDN sufficiently ablated sympathetic nerves along renal arteries, demonstrating the safety and efficacy of the approach and the novel device."
"Cryoablation for Renal Denervation:
A Cool Alternative to Thermal Approaches?"
"Their preclinical study in a porcine model demonstrates the feasibility and efficacy of a nitrous oxide–based cryoballoon system with a "1-inflation-only" approach that could reduce the multiple ablation points required for the RF or ultrasound RDN system. "
The Silent Killer: Hypertension.
Nearly 25% of the global population is affected by hypertension.
Of those patients, around 25% do not respond adequately to drug therapy and suffer from resistant hypertension. For these non-responders, the consequences are severe: a 20% higher risk of stroke, a 31% increase in intracerebral hemorrhage, and billions in additional healthcare costs worldwide.
Our cold RDN approach with the “Renal Freezer” represents a new therapeutic option for patients with resistant hypertension — designed to deliver a lasting treatment effect in a single, streamlined intervention.

